In 1046, the Byzantine emperor Constantine IX Monomachos (1042-1054), gave his daughter Anna in marriage to Prince Vsevolod Yaroslavich, the son of Yaroslav the Wise. He blessed her on her way with this icon. After the death of Prince Vsevolod the icon went to his son Vladimir Monomachos, who transferred it at the beginning of the twelfth century into the Smolensk cathedral church in honor of the Dormition of the Most Holy Theotokos. From that time, the icon was known as the Smolensk Hodigitria.

In the year 1238, at the bespeaking of the icon, the self-sacrificing Orthodox warrior Mercurius went by night into the camp of Batu and killed many of the enemy, in whose number was their most powerful warrior. Having accepted a martyr's death in battle, he was included by the Church in the ranks of the Saints (November 24).

In the fourteenth century, Smolensk came into the possession of the Lithuanian princes. The daughter of prince Vitovt, Sophia, was given in marriage to the Moscow Great Prince Basil Dimitrievich (1398-1425). In 1398, she brought the Smolensk Icon of the Mother of God with her to Moscow. They set the holy image in the Annunciation cathedral of the Kremlin, on the right side of the Royal Doors.

In 1456, at the request of the inhabitants of Smolensk with Bishop Misael at the head, the icon was solemnly returned to Smolensk in a church procession, and at Moscow there remained two copies. One was put in the Annunciation cathedral, and the other, "a measure for measure," was put in the Novodevichi monastery, founded in memory of the return of Smolensk to Russia. The monastery was built on Devichi Pole (Virgin's Field), where "with many tears" the Muscovites handed over the holy icon to Smolensk. In 1602 an exact copy was painted from the wonderworking icon (in 1666 together with the ancient icon they brought a new copy to Moscow for restoration), which they placed in the tower of the Smolensk fortress wall over the Dneprovsk Gates, under a specially constructed cover. Afterwards, in 1727, a wooden church was built there, and in 1802, a stone church.

The new copy took on the power of the old image, and when the Russian armies left Smolensk on August 5, 1812, they took the icon with them for defense from the enemy forces. On the eve of the Battle of Borodino they carried this icon through the camp, to encourage and inspire the soldiers to great deeds. The ancient image of the Smolensk Hodigitria, taken to the Dormition cathedral on the day of the Battle of Borodino went in procession with the Iveron and Vladimir Icons of the Mother of God through the Belo and Kitai quarters and the Kremlin walls, and then they sent it to the sick and wounded at the Lefortovo palace. After leaving Moscow, the icon was taken to Yaroslavl.

Thus were these sister-icons preserved, and the Mother of God defended Russia through Her icons. After the victory over the enemy forces the Hodigitria Icon was returned to Smolensk together with its glorified copy.

The celebration in honor of this wonderworking icon on July 28 was established in the year 1525 in memory of the return of Smolensk to Russia.

There exist many venerated copies of the Smolensk Hodigitria, for which the celebration is set on this day. There is also a day of celebration for the Smolensk Icon (November 5), glorified in the nineteenth century when this image was returned to Smolensk on the orders of the commander-in-chief of the Russian army M. I. Kutuzov. In memory of the expulsion of the enemy from Russia, it was decided to celebrate this day annually at Smolensk.

The holy icon of the Hodigitria Mother of God is one of the chief holy objects of the Russian Church. Believers have received and do receive from it an abundant help of grace. The Mother of God through Her holy icon intercedes for and strengthens us, guiding us on the way to salvation, and we call out to Her, "Thou art the All-Blessed Hodigitria for faithful peoples, Thou art the affirmation, the Praiseworthy of Smolensk and all the Russian land. Rejoice, Hodigitria, salvation of Christians!"